Pilot and Feasibility Program

 

The Pilot and Feasibility Study (P&F) Program provides one year of funding to new investigators or established scientists to provide an opportunity to test new hypotheses, collect preliminary data and develop these projects into a related, independently funded research project. The goal of the P&F program is to encourage investigators outside of skin research to explore projects bringing them into the field. It is imperative that the P&F Studies utilize the epiCURE Core Facilities which provide access to state-of-the-art equipment and services. These pilot grants are intended to support feasibility studies that will establish a basis for applying for further research funding.

ELIGIBILITY REQUIREMENTS

A faculty-level appointment at Columbia University or other institution in the epiCURE research community.

CORES and SERVICES

Stem Cell Imaging and Manipulation Core (SCIM) 

Will provide a wide array of histological, immunohistochemical, and molecular-based tools to characterize gross and microscopic morphology, functional features and gene expression in skin of human and genetically engineered laboratory animals.

Skin Immunity, Integrity and Disease Core (SIND) 

Will offer in vivo and ex vivo models that aim to mimic disease relevant aspects of human skin are essential for understanding normal and pathological skin physiology as well as identification and preclinical proof of concept studies of novel therapies for skin diseases.

Translational and Precision Medicine Resources Core (TRAP) 

Will offer services to facilitate study design and statistical analysis, tissue procurement, biobanking, and with the computational analysis of genomic data. 

PROPOSAL FORMAT

NIH PHS 398 Format. Provide a maximum three (3) page description of the project, an NIH-style biosketch (including other support), a budget, budget justification and a statement of facilities/resources. In addition, provide justification for the use of at least one or more of the cores. 

BUDGET

Individual awards will be made for $20,000 to $30,000 in direct costs for a one year period.

APPLICATION DEADLINE

Applications are due by 5:00pm on  Friday, May 15, 2020

SUBMISSION

Submit a digital copy of your proposal to: [email protected]

APPROXIMATE START DATE

July 1, 2020

INTERESTED INVESTIGATORS ARE ENCOURAGED TO CONTACT

Angela Christiano, PhD: [email protected]

David Owens, PhD: [email protected]

See also: https://epicure.cumc.columbia.edu/content/pilot-and-feasibility-program-0

*This program is funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases under award number 5P30AR069632.

 

Pilot and Feasibility Award Program

2019-2020 Awardees

  • Dr. Adolfo Ferrando - Department of Institute for Cancer Genetics - Title "The Role of TINCR in Skin homoeostasis and aging" - Award Amount - $25,000
  • Dr. Sarah Millar - Department of Icahn School of Medicine at Mt. Sinai - Title "Development of a platform for screening and testing new therapeutics for ectodermal dysplasia in patients with WNT10A mutations" - Award Amount - $25,000

2018-2019 Awardees

  • Dr. Alice Prince - Dermatology of Pediatrics - Title "Host factors that provide immunity to S. aureus skin infection" - Award Amount - $30,000
  • Dr. Lynn Petukhova - Dermatology of Department - Title "Initiating translational genetic studies in hidradenitis suppurativa" -  Award Amount - $20,000

2017-2018 Awardees

  • Dr. David Owens - Dermatology of Department - Title "Age-related deficits in the Merkel lineage and touch sensitivity" - Award Amount - $50,000

2016-2017 Awardees

  • Dr. Arianna Kim - Dermatology of Department - Title "The Role of mTOR-SIRT1 signaling in UV- induced senescence induction" - Award Amount - $50,000